Driving in Cairo is hectic and to the unfamiliar, challenging. Cairo subway known as the metro is excellent for getting around. The buses on the other hand could be somewhat confusing to visitors to Cairo. Your best bet would be to rent a chauffeur driven car, the rates are very reasonable, and you can get around without having to worry about traffic, directions or parking.

Cairo is also a fascinating walking city but be aware that crossing the streets will need some courage. Just keep those rules in mind, stay close to the locals and cross when they do, when started keep going, do not stop and freeze in the middle of traffic.

Another pleasant alternative is to take a river taxi, they leave from various docks and you can ask your hotel concierge or friends where the nearest dock is to you.
Street taxis are also plentiful, cheap and easy to hail. For clean air conditioned cabs, look for the bright yellow cabs. They cost a little bit more but you may find them well worth it.